Chalti ka naan Gaadi is a story about three brothers Brijmohan Sharma [Ashok Kumar], Jagmohan Sharma [ Anoop Kumar] and Manmohan Sharma [Kishore Kumar] who own a garage.The eldest brother Brjmohan alias Birju hates women and he protects his younger brothers from falling prey to girls. On one rainy night a beautiful girl Renu [Madhubala] comes to the garage to get her car repaired. Here she meets Manmohan and an interesting love story develops between the two. On the other hand, a con man Raja Hardayal [K.N.Sigh] hatches a plot to get his man Prakash [Sajjan] marry Renu and then get her property. Birju is against Mannu & Renu's affair . The story takes a turn when Birju's past love affair is disclosed whch has got some ties with Raja Hardayal and many secrets are revealed.