Born and raised in the Bronx, New York, James made his first appearance on November 22, 1975 for parents Gerard and Nancee. He is one of seven children. At the age of thirteen with his very first audition, James landed a role in the Steven Spielberg family adventure, 'Hook' (1991) and never looked back. On the set of Hook, Dustin Hoffman was impressed enough with Madio's talent to suggest him for the role of his son in the film 'Hero' (1992/I). The same year, he appeared as the younger version of the title character in the Independent film 'Mac' (1992), starring John Turturro (in his directorial debut). James then went to star along side Leonardo DiCaprio and Mark Wahlberg in the acclaimed 'The Basketball Diaries' (1995). James ventured into the independent film world, accepting lead roles in movies such as 'The Gifted' (1999) in which he played a naturally gifted violinist and 'If Tomorrow Comes' (2000) as the mentally challenged younger brother of 'James Franco'. His strive for more led him to his second tour with Spielberg, in arguably the best mini-series of all time, HBO's "Band of Brothers" (2001). He also worked quite a bit in television, appearing in episodes of "Bones" (2005), "C.S.I Miami" (2002), "Cold Case" (2003), "Arli$$" (1996), "Las Vegas" (2003) and "Jag" (1995). James lent his voice in DreamWorks Blockbuster animated movie 'Shark Tale' (2004) and also in the Call of Duty (2003) (vg) video game franchise. Other Independent works include, 'The Box' (2007/II), which he co-produced, and 'Love Lies Bleeding' (2008), starring Christian Slater. 'Searching for Bobby D' (2005), 'West of Brooklyn' (2008), 'Dough Boys' (2008) and 'The Grasslands' (2011). In 2009, James stepped behind the camera and directed 'Baby Bomber' (2009) a short comedy about a Bronx Little League Slugger to big for his size. Baby Bomber was selected to a number of film festivals, including winning the audience choice award at the Kent Film Festival. His most recent works include, executed anarchist Nicola Sacco in the feature film 'No God No Master' (2010) due out in 2011 and 'Desert Rain' (2011), an official selection of the Cinequest Film Festival. James is in post production on an ambitious short film titled 'AppleBox' (2011) in which he wrote, produced and starred in. James resides in California where he continues to build on his success.