Monu Mukhopadhay was born on 1st March, 1930. He passed his matriculation from Bharati Vidyalaya in 1946. In 1948 , he completed his IA from Monindra College. He is a good football player and has learnt tabla from Krishnakumar Ganguly.
In 1959, he made his debut in Mrinal Sen’s “Neel Akasher Niche” in a small role. Although he was a very talented actor with high potential, directors and producers have never given him the chance to do the lead roles in the films. Sesh theke Shuru (1961) , Ashni sanket(1973) , Koroti (1988) are some of his noteworthy films. He is a professional stage artist who is involved with Rupkar theatre group. He used to work as a promoter in Biswarupa theatre and got a chance to work in their famous theatre production, Khuda in the absence of Kali Banerjee. He is also a radio and television artist.