No Problem trails the misadventures of Yash Ambani (Sanjay Dutt) and Raj Ambani (Akshaye Khanna), two childhood friends and small time crooks. Raj contemplates changing tracks and leaving the world of crime. Yash on the other hand always manages to do something which closes all doors for Raj to change his life. After these two engage in their latest bank robbery, Zandulal (Paresh Rawal), the bank manager, is accused as their accomplice. Zabdulal is now on a quest to prove his innocence.
In the meanwhile, Raj falls in love with Sanjana (Kangna Ranaut), who is the younger sister of Kajal (Sushmita Sen), the daughter of the Comissioner of Police (Shakti Kapoor) and the wife of Arjun Singh (Anil Kapoor), a cop. What then follows is a hilarious trail of love, missing diamonds and the mysterious murder of a white collared mafia.
Who did the murder? Where are the diamonds? Will Yash, Raj and Zandulal be able to prove their innocence? Check out in this hilarious ‘whodunit’, as No Problem gears up to hit the big screens.