The movie is about a mix of people who are trying to leave for the U.S. and their stories which have a surprising link.
Salim Rajabali (Irrfan Khan) is a stock broker. He and his brother, Javed, inadvertently get implicated in the murder of Deputy Commissioner of Police, Paul, and Salim must flee immediately to the U.S. albeit with a heavy heart, after also being betrayed by his lover, Namrata (Suhasini Mule).
Rajubhai Patel (Paresh Rawal) who runs foreign shows and takes along Payal, who is the daughter of an old flame Tara (Ratna Pathak Shah) , who is now fated to live with an alcoholic husband and do minor acting roles in Bollywood movies.
Brilliant student Rahul Bhide (Ankur Khanna) who lives with his aged dad, in a dilapidated house, finds his future looking brighter when his dad passes away. He is leaving for the U.S. to pursue his dreams, further studies.
Tilotamma Das (Konkona Sen Sharma) who met and married Hemant Punj (Jimmy Shergill) is now awaiting the arrival of her visa, to join her husband in the U.S., when she finds she cannot take any more from her pushy mother-in-law.
All of them try to reach America.